A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C.

• Main Authors: Federico Napolitano (Author), Rossella Merone (Author), Adele Abbate (Author), Virginia Ammendola (Author), Emma Horncastle (Author), Francesca Lanzaro (Author), Marialuisa Esposito (Author), Alessandra Maria Contino (Author), Roberta Sbrocchi (Author), Andrea Sommella (Author), Joshua D Duncan (Author), Jospeh Hinds (Author), Richard A Urbanowicz (Author), Armin Lahm (Author), Stefano Colloca (Author), Antonella Folgori (Author), Jonathan K Ball (Author), Alfredo Nicosia (Author), Benjamin Wizel (Author), Stefania Capone (Author), Alessandra Vitelli (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rabies, caused by RNA viruses in the Genus Lyssavirus, is the most fatal of all infectious diseases. This neglected zoonosis remains a major public health problem in developing countries, causing the death of an estimated 25,000-159,000 people each year, with more than half of them in children. The...