Cover Image

Metformin Mitigates Sepsis-Induced Acute Lung Injury and Inflammation in Young Mice by Suppressing the S100A8/A9-NLRP3-IL-1β Signaling Pathway

Shi-Yuan Fan,1,&ast; Zi-Chi Zhao,1,&ast; Xing-Lv Liu,1 Ying-Gang Peng,1 Hui-Min Zhu,1 Shi-Fan Yan,2 Yan-Juan Liu,2 Qin Xie,2 Yu Jiang,2 Sai-Zhen Zeng1 1The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, People's R...

Full description

Saved in:

Bibliographic Details
Main Authors:	Fan SY (Author), Zhao ZC (Author), Liu XL (Author), Peng YG (Author), Zhu HM (Author), Yan SF (Author), Liu YJ (Author), Xie Q (Author), Jiang Y (Author), Zeng SZ (Author)
Format:	Book
Published:	Dove Medical Press, 2024-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
by: Yi Liu, et al.
Published: (2018)

Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation
by: Li N, et al.
Published: (2021)

Protective Effect of Metformin on Sepsis Myocarditis in Zebrafish
by: Mingming Zhang, et al.
Published: (2020)

Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury
by: Haiyan Li, et al.
Published: (2022)

Metformin can mitigate skeletal dysplasia caused by Pck2 deficiency
by: Zheng Li, et al.
Published: (2022)

The Contribution of S100B Suppression by Arundic Acid to the Inhibition of the Glio-Toxicity Induced by Beta-Amyloid in an Astrocytes Culture
by: Mahshid Hosseini, et al.
Published: (2019)

Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis
by: Bo Cheng, et al.
Published: (2022)

Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis
by: Bo Cheng, et al.
Published: (2022)

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
by: Jia Zhao, et al.
Published: (2023)

Correction: Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis
by: Bo Cheng, et al.
Published: (2022)

Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome
by: Qing Hou, et al.
Published: (2022)

Anisodamine Suppressed the Growth of Hepatocellular Carcinoma Cells, Induced Apoptosis and Regulated the Levels of Inflammatory Factors by Inhibiting NLRP3 Inflammasome Activation
by: Li P, et al.
Published: (2020)

Shenfu Injection Mediated NLRP3/Caspase 1 Through (R)-Norcoclaurinee Alleviates Sepsis-Induced Cognitive Dysfunction
by: Liu X, et al.
Published: (2024)

HDAC5-Mediated Acetylation of p100 Suppresses Its Processing
by: Jianqi Wang, et al.
Published: (2023)

Efficacy of beta-blockers in the treatment of sepsis
by: Peng Jin, et al.
Published: (2021)

Metformin Mitigates Fibrosis and Glucose Intolerance Induced by Doxorubicin in Subcutaneous Adipose Tissue
by: Luana A. Biondo, et al.
Published: (2018)

Co-administration of Spondias mombin and Metformin mitigates Streptozotocin-induced hepatorenal injury
by: Bala Peter Akwu, et al.
Published: (2022)

Berberine Mitigates Sepsis-Associated Acute Kidney Injury in Aged Rats by Preserving Mitochondrial Integrity and Inhibiting TLR4/NF-κB and NLRP3 Inflammasome Activations
by: Ruedeemars Yubolphan, et al.
Published: (2024)

Role of IRF4 in the Protection of Metformin-Mediated Sepsis Myocarditis
by: Minghua Li, et al.
Published: (2019)

Ilex pubescens inhibits pyroptosis post-myocardial infarction through suppression of the ROS/NLRP3 pathway
by: Ting-fang Chen, et al.
Published: (2024)

Metformin Mitigates Cartilage Degradation by Activating AMPK/SIRT1-Mediated Autophagy in a Mouse Osteoarthritis Model
by: Chenzhong Wang, et al.
Published: (2020)

Inhibition of EGFR Pathway Suppresses M1 Macrophage Polarization and Osteoclastogenesis, Mitigating Titanium Particle-Induced Bone Resorption
by: Jia Q, et al.
Published: (2024)

Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome
by: Hefei Huang, et al.
Published: (2024)

Modeling of suppression and mitigation interventions in the COVID-19 epidemics
by: Yuexing Han, et al.
Published: (2021)

Thymol Isolated from Thymus vulgaris L. Inhibits Colorectal Cancer Cell Growth and Metastasis by Suppressing the Wnt/β-Catenin Pathway
by: Zeng Q, et al.
Published: (2020)

Zerumbone Suppresses the LPS-Induced Inflammatory Response and Represses Activation of the NLRP3 Inflammasome in Macrophages
by: Chia-Cheng Su, et al.
Published: (2021)

Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice
by: Lieliang Zhang, et al.
Published: (2021)

Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation
by: Qiu-Meng Xie, et al.
Published: (2023)

Metformin and/or vildagliptin mitigate type II diabetes mellitus induced-oxidative stress: The intriguing effect
by: Hayder M Al-Kuraishy, et al.
Published: (2020)

Autoimmune Thyroiditis Mitigates the Effect of Metformin on Plasma Prolactin Concentration in Men with Drug-Induced Hyperprolactinemia
by: Robert Krysiak, et al.
Published: (2024)

Acute Lung Injury and the NLRP3 Inflammasome
by: Gu W, et al.
Published: (2024)

Doxycycline Attenuates Cancer Cell Growth by Suppressing NLRP3-Mediated Inflammation
by: Mohammad Alsaadi, et al.
Published: (2021)

Hydroxy-Safflower Yellow A Mitigates Vascular Remodeling in Rat Pulmonary Arterial Hypertension
by: Ji XY, et al.
Published: (2024)

Role of Cellular Senescence Genes and Immune Infiltration in Sepsis and Sepsis-Induced ARDS Based on Bioinformatics Analysis
by: Wu XL, et al.
Published: (2024)

Yanghe Decoction Suppresses the Experimental Autoimmune Thyroiditis in Rats by Improving NLRP3 Inflammasome and Immune Dysregulation
by: Bing'e Ma, et al.
Published: (2021)

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis
by: Ruidong Li, et al.
Published: (2016)

The Role of Agriculture and Foreign Remittances in Mitigating Rural Poverty: Empirical Evidence from Pakistan
by: Liu Y, et al.
Published: (2020)

Bitongqing Attenuates CIA Rats by Suppressing Macrophage Pyroptosis and Modulating the NLRP3/Caspase-1/GSDMD Pathway
by: Wu Y, et al.
Published: (2024)

The Antimalarial Chloroquine Suppresses LPS-Induced NLRP3 Inflammasome Activation and Confers Protection against Murine Endotoxic Shock
by: Xiaoli Chen, et al.
Published: (2017)

The Potential of Drug Delivery Nanosystems for Sepsis Treatment
by: Shi Y, et al.
Published: (2021)