Prognostic factors for low birthweight repetition in successive pregnancies: a cohort study

• Main Authors: Sclowitz Iândora Krolow Timm (Author), Santos Iná S (Author), Domingues Marlos Rodrigues (Author), Matijasevich Alicia (Author), Barros Aluísio J D (Author)
• Format: Book
• Published: BMC, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.1186/1471-2393-13-20; 1471-2393
• Keywords: Prognostic factors; Low birthweight recurrence; Low birthweight; Preterm; Antenatal care; Gynecology and obstetrics; RG1-991
• Source: BMC Pregnancy and Childbirth, Vol 13, Iss 1, p 20 (2013)

<p>Abstract</p> <p>Background</p> <p>To identify prognostic factors associated with recurrence of low birthweight (LBW) in successive gestations, a study was carried out with a subsample of mothers enrolled in the 2004 Pelotas Birth Cohort.</p> <p>Methods</p> <p>Data were collected by hospital-based interviews. Newborns were weighed and measured. Gestational age was defined according to the date of last menstrual period, ultra-sound scan before the 20^th week of pregnancy or the Dubowitz method. Mothers who reported at least one LBW newborn in the two previous gestations were included. Prevalence ratios (PR) and 95% confidence intervals were estimated from Poisson Regression. All estimates were adjusted for parity.</p> <p>Results</p> <p>A total of 4558 births were identified in 2004, and 565 met inclusion criteria, out of which 86 (15.2%) repeated LBW in 2004. Among mothers with two LBW babies before 2004, 47.9% presented LBW recurrence. Belonging to the highest socio-economic stratum (PR 0.89; 0.01-0.46) and gaining ≥ 10 kg during pregnancy (PR 0.09; 0.01-0.77) were protective against LBW recurrence. Higher risk of LBW recurrence was observed among mothers with higher parity (≥3 previous deliveries; PR=1.93; 95% CI 1.23-3.02); who had given birth to a previous preterm baby (PR=4.01; 2.27-7.10); who delivered a female newborn in current gestation (PR=2.61; 1.45-4.69); and that had not received adequate antenatal care (PR=2.57; 1-37-4.81).</p> <p>Conclusion</p> <p>Improved quality of antenatal care and adequate maternal weight gain during pregnancy may be feasible strategies to prevent LBW repetition in successive pregnancies.</p>