Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a case of a 79 years old male, subjected to transurethral resection of bladder tumor, which histological examination revealed a pT1 high-grade urothelial carc...

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Main Authors: Rui Pedro C. M. Oliveira (Author), Carlos Filipe C. Abrantes (Author), Edgar Miguel C. T. Silva (Author), Carol A. Marinho (Author), Vítor Manuel L. Sousa (Author), Lígia R. C. O. A. P. Castro (Author)
Format: Book
Published: Sociedade Brasileira de Patologia Clínica.
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Summary:ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a case of a 79 years old male, subjected to transurethral resection of bladder tumor, which histological examination revealed a pT1 high-grade urothelial carcinoma. Subsequently, he underwent radical cystoprostatectomy, which showed urothelial carcinoma with lack of cohesion, plasmacytoid variant, positive for citokeratin 7 (CK7), citokeratin 20 (CK20) and trans-acting T-cell-specific transcription factor (GATA-3), and negative for E-cadherin and CD138. It is important to recognize the plasmacytoid variant of the invasive urothelial carcinoma, since it avoids a potential misdiagnosis of metastatic cancer.
Item Description:1676-2444
1678-4774
10.5935/1676-2444.20160043