Application of glucocorticoids in patients with novel coronavirus infection: From bench to bedside

Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors an...

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Bibliographic Details
Main Authors: Linwei Lu (Author), Jianhua Huang (Author), Xiaohong Deng (Author), Xianjun Sun (Author), Jingcheng Dong (Author)
Format: Book
Published: World Scientific Publishing, 2020-12-01T00:00:00Z.
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Summary:Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors and clinical applications in COVID-19. Through reviewing the current literature, our aim is to have a deeper understanding of the mechanism of GCs and their clinical applications, so as to find possible ways to enhance their efficacy and reduce drug resistance or side effects.
Item Description:2575-9000
2575-9019
10.1142/S257590002030009X