Application of glucocorticoids in patients with novel coronavirus infection: From bench to bedside

Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors an...

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Main Authors: Linwei Lu (Author), Jianhua Huang (Author), Xiaohong Deng (Author), Xianjun Sun (Author), Jingcheng Dong (Author)
Format: Book
Published: World Scientific Publishing, 2020-12-01T00:00:00Z.
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100 1 0 |a Linwei Lu  |e author 
700 1 0 |a Jianhua Huang  |e author 
700 1 0 |a Xiaohong Deng  |e author 
700 1 0 |a Xianjun Sun  |e author 
700 1 0 |a Jingcheng Dong  |e author 
245 0 0 |a Application of glucocorticoids in patients with novel coronavirus infection: From bench to bedside 
260 |b World Scientific Publishing,   |c 2020-12-01T00:00:00Z. 
500 |a 2575-9000 
500 |a 2575-9019 
500 |a 10.1142/S257590002030009X 
520 |a Glucocorticoids (GCs) have potential anti-inflammatory and immunosuppressive effects. There is plenty of controversy about the application of glucocorticoids in the treatment of coronavirus disease 2019 (COVID-19). This paper briefly summarizes the mechanism of glucocorticoids and their receptors and clinical applications in COVID-19. Through reviewing the current literature, our aim is to have a deeper understanding of the mechanism of GCs and their clinical applications, so as to find possible ways to enhance their efficacy and reduce drug resistance or side effects. 
546 |a EN 
690 |a glucocorticoids 
690 |a glucocorticoid receptor 
690 |a glucocorticoid resistance 
690 |a respiratory system 
690 |a covid-19 
690 |a Other systems of medicine 
690 |a RZ201-999 
655 7 |a article  |2 local 
786 0 |n Traditional Medicine and Modern Medicine, Vol 3, Iss 4, Pp 255-268 (2020) 
787 0 |n http://www.worldscientific.com/doi/epdf/10.1142/S257590002030009X 
787 0 |n https://doaj.org/toc/2575-9000 
787 0 |n https://doaj.org/toc/2575-9019 
856 4 1 |u https://doaj.org/article/ecb55a3e3f4f4cdf8cfff1b47fecfedc  |z Connect to this object online.