SYNTHESES AND ANTIOXIDANT ACTIVITIES OF SOME HYDROXY DIMETHOXY CHALCONE DERIVATIVES
Four (4) hydroxy dimethoxy chalcones derivatives were synthesized by Claisen-Schmidt condensation of hydroxyacetophenone with 3,4-dimethoxybenzaldehyde using conventional method and grinding technique. The synthesized compounds were characterized by spectroscopy (IR, 1H-NMR and 13C-NMR). Synthesis o...
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| Aineistotyyppi: | Kirja |
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Universitas Gadjah Mada,
2014-01-01T00:00:00Z.
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| 042 | |a dc | ||
| 100 | 1 | 0 | |a Elfi Susanti VH |e author |
| 700 | 1 | 0 | |a Sabirin Matsjeh |e author |
| 700 | 1 | 0 | |a Mustofa |e author |
| 700 | 1 | 0 | |a Tri Redjeki |e author |
| 700 | 1 | 0 | |a Tutik Dwi Wahyuningsih |e author |
| 245 | 0 | 0 | |a SYNTHESES AND ANTIOXIDANT ACTIVITIES OF SOME HYDROXY DIMETHOXY CHALCONE DERIVATIVES |
| 260 | |b Universitas Gadjah Mada, |c 2014-01-01T00:00:00Z. | ||
| 500 | |a 10.14499/indonesianjpharm25iss1pp17 | ||
| 500 | |a 2338-9427 | ||
| 500 | |a 2338-9486 | ||
| 520 | |a Four (4) hydroxy dimethoxy chalcones derivatives were synthesized by Claisen-Schmidt condensation of hydroxyacetophenone with 3,4-dimethoxybenzaldehyde using conventional method and grinding technique. The synthesized compounds were characterized by spectroscopy (IR, 1H-NMR and 13C-NMR). Synthesis of the hydroxy dimethoxy chalcone using grinding method is better than the conventional method. The synthesis using grinding method require a low concentration base, shorter reaction (15min) and higher yield (70-84%). The antioxidant activity of the compounds was determined by DPPH method, showed that 2',5'-dihydroxy-3,4-dimethoxy chalcone have the highest antioxidant activity. | ||
| 546 | |a EN | ||
| 690 | |a hydroxy dimethoxy chalcone | ||
| 690 | |a Claisen-Schmidt condensation | ||
| 690 | |a grinding | ||
| 690 | |a DPPH method | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Indonesian Journal of Pharmacy, Vol 25, Iss 1, Pp 17-24 (2014) | |
| 787 | 0 | |n http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/14 | |
| 787 | 0 | |n https://doaj.org/toc/2338-9427 | |
| 787 | 0 | |n https://doaj.org/toc/2338-9486 | |
| 856 | 4 | 1 | |u https://doaj.org/article/ecb5c61c0d4d44c49ec3d2252646dfb4 |z Connect to this object online. |