Squamous cell carcinoma developed on inflammatory dermatoses followed at a tertiary hospital, between the years 2000 and 2020

• Main Authors: Luana Rampazzo Magalhães (Author), Thais Helena Buffo (Author), Elemir Macedo de Souza (Author), Renata Ferreira Magalhães (Author), Andréa Fernandes Eloy da Costa França (Author), Rafael Fantelli Stelinit (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia (SBD), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

INTRODUCTION: The advent of squamous cell carcinomas (SCC) from chronic dermatoses is known but little explored. Although rare, tumors originating there have a worse prognosis, in part due to late diagnosis. OBJECTIVES: This study aims to survey cases of squamous cell carcinoma developed on previous dermatoses diagnosed between 2000 and 2020 in a tertiary health service. METHODS: This is a quantitative and retrospective study through biopsy reports survey and medical records review. RESULTS: From an initial list of 11,249 histological reports compatible with squamous cell carcinoma, we obtained a final list of 10 patients. The study findings corroborate the literature regarding some known risk factors: abundant and chronic sun exposure, older than 50 years, lower skin phototypes, and immunosuppression. We also found a high frequency of smoking and lichenoid dermatoses (5/10 patients) in the studied population, including chronic cutaneous lupus erythematosus and hypertrophic lichen planus. CONCLUSIONS: It is not possible to predict the primary risk factors for the development of squamous cell carcinomas regarding previous dermatoses, although there is a tendency for their appearance in lichenoid dermatoses and those with longer evolution.

Item Description

1984-8773
10.5935/scd1984-8773.2023150248