Targeting murine alveolar macrophages by the intratracheal administration of locked nucleic acid containing antisense oligonucleotides

The pulmonary delivery of locked nucleic acid containing antisense oligonucleotides (LNA-ASOs) is expected to be a novel therapeutic approach for lung diseases. However, there are two concerns to be considered: immune responses, as the lung has a distinct immune mechanism to protect it from inhaled...

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Autors principals: Yasunori Uemura (Autor), Katsuya Kobayashi (Autor)
Format: Llibre
Publicat: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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