Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line

• Үндсэн зохиолчид: Myriam González (Зохиогч), María Ovejero-Sánchez (Зохиогч), Alba Vicente-Blázquez (Зохиогч), Manuel Medarde (Зохиогч), Rogelio González-Sarmiento (Зохиогч), Rafael Peláez (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Thirty seven N-(5-methoxyphenyl)-4-methoxybenzenesulphonamide with methoxy or/and bromo substitutions (series 1-4) and with different substituents on the sulphonamide nitrogen have been synthesised. 21 showed sub-micromolar cytotoxicity against HeLa and HT-29 human tumour cell lines, and were partic...