Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line

• Những tác giả chính: Myriam González (Tác giả), María Ovejero-Sánchez (Tác giả), Alba Vicente-Blázquez (Tác giả), Manuel Medarde (Tác giả), Rogelio González-Sarmiento (Tác giả), Rafael Peláez (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Thirty seven N-(5-methoxyphenyl)-4-methoxybenzenesulphonamide with methoxy or/and bromo substitutions (series 1-4) and with different substituents on the sulphonamide nitrogen have been synthesised. 21 showed sub-micromolar cytotoxicity against HeLa and HT-29 human tumour cell lines, and were partic...