Prophylactic effect of Amiodarone and in combination with vitamin C in reducing atrial fibrillation after coronary artery bypass

Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery, leading to hemodynamic impairment and increased mortality and morbidity after coronary artery bypass grafting (CABG) and increases hospitalization. Due to the antioxidant and anti-inflammatory effects of vitamin C as w...

Full description

Saved in:
Bibliographic Details
Main Authors: Alireza Kamali (Author), Samira Yavari (Author), Bijan Yazdi (Author), Alireza Rostami (Author)
Format: Book
Published: PAGEPress Publications, 2021-09-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_ed65ddf519a24d1a9d66e48adb4c0e06
042 |a dc 
100 1 0 |a Alireza Kamali  |e author 
700 1 0 |a Samira Yavari  |e author 
700 1 0 |a Bijan Yazdi  |e author 
700 1 0 |a Alireza Rostami  |e author 
245 0 0 |a Prophylactic effect of Amiodarone and in combination with vitamin C in reducing atrial fibrillation after coronary artery bypass 
260 |b PAGEPress Publications,   |c 2021-09-01T00:00:00Z. 
500 |a 10.4081/ejtm.2021.8981 
500 |a 2037-7452 
500 |a 2037-7460 
520 |a Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery, leading to hemodynamic impairment and increased mortality and morbidity after coronary artery bypass grafting (CABG) and increases hospitalization. Due to the antioxidant and anti-inflammatory effects of vitamin C as well as the antiarrhythmic effect of amiodarone in reducing the incidence of atrial fibrillation after coronary artery bypass grafting, we decided to compare and evaluate the prophylactic effect of amiodarone alone and in combination with vitamin C in controlling this complication. In this double-blind clinical trial, patients were divided into two equal groups of amiodarone (300 mg amiodarone bolus during 20-30 minutes) and amiodarone + vitamin C (150 mg amiodarone and 2g vitamin C combination). Each group included 42 patients. All data were analyzed by SPSS 19 software and statistical tests of ANOVA, Chi-square and Repeated Measure. There was a significant difference between the two groups of amiodarone and amiodarone+vitamin C (p-value = 0.01) and the mean incidence of AF in the amiodarone +vitamin C group was significantly lower than that of amiodarone alone. Other arrhythmias were also lower in the amiodarone +vitamin C group than in the amiodarone group alone. The use offibrillation after CABG compared with prophylactic amiodarone alone, but did not have a significant effect on decreasing ICU stay(discharge) and duration of hospitalization. 
546 |a EN 
690 |a Amiodarone 
690 |a atrial fibrillation 
690 |a prophylaxis 
690 |a vitamin C 
690 |a Medicine 
690 |a R 
690 |a Human anatomy 
690 |a QM1-695 
655 7 |a article  |2 local 
786 0 |n European Journal of Translational Myology (2021) 
787 0 |n https://www.pagepressjournals.org/index.php/bam/article/view/8981 
787 0 |n https://doaj.org/toc/2037-7452 
787 0 |n https://doaj.org/toc/2037-7460 
856 4 1 |u https://doaj.org/article/ed65ddf519a24d1a9d66e48adb4c0e06  |z Connect to this object online.