Advances in targeting cancer-associated fibroblasts through single-cell spatial transcriptomic sequencing

• Main Authors: Pin Lyu (Author), Xiaoming Gu (Author), Fuqi Wang (Author), Haifeng Sun (Author), Quanbo Zhou (Author), Shuaixi Yang (Author), Weitang Yuan (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and are related to tumor proliferation, metastasis, relapse, and drug resistance. With the development of sequencing technologies, single-cell RNA sequencing has become a popular method for identifyi...