Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats

• Main Authors: Barbara Szeiffova Bacova (Author), Csilla Viczenczova (Author), Katarina Andelova (Author), Matus Sykora (Author), Kiranj Chaudagar (Author), Miroslav Barancik (Author), Michaela Adamcova (Author), Vladimir Knezl (Author), Tamara Egan Benova (Author), Peter Weismann (Author), Jan Slezak (Author), Narcisa Tribulova (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac β-adrenergic overstimulation results in oxidative stress, hypertrophy, ischemia, lesion, and fibrosis rendering the heart vulnerable to malignant arrhythmias. We aimed to explore the anti-arrhythmic efficacy of the anti-oxidative and anti-inflammatory compounds, melatonin, and omega-3, and t...