Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against <i>Staphylococcus aureus</i>

• Κύριοι συγγραφείς: Maria V. Golikova (Συγγραφέας), Elena N. Strukova (Συγγραφέας), Yury A. Portnoy (Συγγραφέας), Stephen H. Zinner (Συγγραφέας), Alexander A. Firsov (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2020-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

To explore whether susceptibility testing with antibiotic combinations at pharmacokinetically derived concentration ratios is predictive of the antimicrobial effect, a <i>Staphylococcus aureus</i> strain was exposed to daptomycin and gentamicin alone or in combination in multiple dosing...