Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside.
<h4>Background</h4>To accelerate the progress towards onchocerciasis elimination, a macrofilaricidal drug that kills the adult parasite is urgently needed. Emodepside has shown macrofilaricidal activity against a variety of nematodes and is currently under clinical development for the tr...
Saved in:
Main Authors: | Frauke Assmus (Author), Richard M Hoglund (Author), Frédéric Monnot (Author), Sabine Specht (Author), Ivan Scandale (Author), Joel Tarning (Author) |
---|---|
Format: | Book |
Published: |
Public Library of Science (PLoS),
2022-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside
by: Frauke Assmus, et al.
Published: (2022) -
Medication adherence framework: A population‐based pharmacokinetic approach and its application in antimalarial treatment assessments
by: Junjie Ding, et al.
Published: (2024) -
Diethylcarbamazine increases activation of voltage-activated potassium (SLO-1) currents in Ascaris suum and potentiates effects of emodepside.
by: Samuel K Buxton, et al.
Published: (2014) -
Onchocerciasis Drug Discovery: In Vitro Evaluation of FDA-Approved Drugs against <i>Onchocerca gutturosa</i> in Gambia
by: Suzanne Gokool, et al.
Published: (2024) -
Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside.
by: Daniel Kulke, et al.
Published: (2014)