Mechanism Involved in Acute Liver Injury Induced by Intestinal Ischemia-Reperfusion
Intestinal ischemia-reperfusion (I/R) is a common pathophysiological process, which can occur in many conditions such as acute enteric ischemia, severe burns, small intestinal transplantation, etc,. Ischemia-reperfusion of the intestine is often accompanied by distal organ injury, especially liver i...
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Frontiers Media S.A.,
2022-05-01T00:00:00Z.
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| 001 | doaj_eddf5f9ddf274813a62f3dd1eb7cc86d | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Binghui Jin |e author |
| 700 | 1 | 0 | |a Binghui Jin |e author |
| 700 | 1 | 0 | |a Guangyao Li |e author |
| 700 | 1 | 0 | |a Guangyao Li |e author |
| 700 | 1 | 0 | |a Lin Zhou |e author |
| 700 | 1 | 0 | |a Zhe Fan |e author |
| 700 | 1 | 0 | |a Zhe Fan |e author |
| 245 | 0 | 0 | |a Mechanism Involved in Acute Liver Injury Induced by Intestinal Ischemia-Reperfusion |
| 260 | |b Frontiers Media S.A., |c 2022-05-01T00:00:00Z. | ||
| 500 | |a 1663-9812 | ||
| 500 | |a 10.3389/fphar.2022.924695 | ||
| 520 | |a Intestinal ischemia-reperfusion (I/R) is a common pathophysiological process, which can occur in many conditions such as acute enteric ischemia, severe burns, small intestinal transplantation, etc,. Ischemia-reperfusion of the intestine is often accompanied by distal organ injury, especially liver injury. This paper outlined the signal pathways and cytokines involved in acute liver injury induced by intestinal I/R: the NF-κB Signaling Pathway, the P66shc Signaling Pathway, the HMGB1 Signaling Pathway, the Nrf2-ARE Signaling Pathway, the AMPK-SIRT-1 Signaling Pathway and other cytokines, providing new ideas for the prevention and treatment of liver injury caused by reperfusion after intestinal I/R. | ||
| 546 | |a EN | ||
| 690 | |a intestinal ischemia-reperfusion | ||
| 690 | |a acute liver injury | ||
| 690 | |a mechanism | ||
| 690 | |a signal transduction pathways | ||
| 690 | |a treatment | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pharmacology, Vol 13 (2022) | |
| 787 | 0 | |n https://www.frontiersin.org/articles/10.3389/fphar.2022.924695/full | |
| 787 | 0 | |n https://doaj.org/toc/1663-9812 | |
| 856 | 4 | 1 | |u https://doaj.org/article/eddf5f9ddf274813a62f3dd1eb7cc86d |z Connect to this object online. |