Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives

1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole, and 1,2,3-oxadiazole. This nucleus has variou...

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Main Authors: Shailesh Pathak (Author), Sharad Sharma (Author), Vinay Pathak (Author), Mahesh Prasad (Author)
Format: Book
Published: Creative Pharma Assent, 2020-11-01T00:00:00Z.
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100 1 0 |a Shailesh Pathak  |e author 
700 1 0 |a Sharad Sharma  |e author 
700 1 0 |a Vinay Pathak  |e author 
700 1 0 |a Mahesh Prasad  |e author 
245 0 0 |a Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives 
260 |b Creative Pharma Assent,   |c 2020-11-01T00:00:00Z. 
500 |a 2348-0335 
500 |a 10.18231/j.joapr.2020.v.8.i.4.50.61 
520 |a 1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole, and 1,2,3-oxadiazole. This nucleus has various biological activity such as antioxidant, antimicrobial, antifungal, antitumor, antidepressant, anticancer, analgesic etc.  have been reported. A series of 1,3,4-oxadiazoles-2(3H)thione derivative has been synthesized in four steps and the derivative were characterized by FTIR spectral analysis. This article explain the different biological activities associated with 1,3,4-oxadiazole five membered ring are useful for researchers across the world working on this nucleus. 
546 |a EN 
690 |a 1,3,4-oxadiazoles 
690 |a syntheses 
690 |a characterization 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Journal of Applied Pharmaceutical Research, Vol 8, Iss 4, Pp 50-61 (2020) 
787 0 |n https://japtronline.com/index.php/joapr/article/view/179 
787 0 |n https://doaj.org/toc/2348-0335 
856 4 1 |u https://doaj.org/article/ee0aedbd6ea04ba0b957e952c56f79c0  |z Connect to this object online.