Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease
Parkinson's disease (PD) is a fatal neurodegenerative disorder that is primarily caused by the degeneration and loss of dopaminergic neurons of the substantia nigra in the ventral midbrain. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of late-onset PD iden...
Saved in:
Main Authors: | Barbara Calamini (Author), Nathalie Geyer (Author), Nathalie Huss-Braun (Author), Annie Bernhardt (Author), Véronique Harsany (Author), Pierrick Rival (Author), May Cindhuchao (Author), Dietmar Hoffmann (Author), Sabine Gratzer (Author) |
---|---|
Format: | Book |
Published: |
The Company of Biologists,
2021-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
by: Joanna A. Korecka, et al.
Published: (2020) -
A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls
by: Maurits F. J. M. Vissers, et al.
Published: (2023) -
Easily misdiagnosed X-linked adrenoleukodystrophy
by: Qiu-Hong Wang, et al.
Published: (2024) -
Easily missed pediatric handlebar injury
by: Po-Shun Wang, et al.
Published: (2023) -
An easily overlooked cause of abdominal pain
by: Kyle Bennett, et al.
Published: (2014)