Immunostimulatory gene therapy combined with checkpoint blockade reshapes tumor microenvironment and enhances ovarian cancer immunotherapy
Immune evasion has made ovarian cancer notorious for its refractory features, making the development of immunotherapy highly appealing to ovarian cancer treatment. The immune-stimulating cytokine IL-12 exhibits excellent antitumor activities. However, IL-12 can induce IFN-γ release and subsequently...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2024-02-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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