Validation of Recombinant Salivary Protein PpSP32 as a Suitable Marker of Human Exposure to Phlebotomus papatasi, the Vector of Leishmania major in Tunisia.

• Main Authors: Soumaya Marzouki (Author), Wafa Kammoun-Rebai (Author), Jihene Bettaieb (Author), Maha Abdeladhim (Author), Saoussen Hadj Kacem (Author), Rania Abdelkader (Author), Sami Gritli (Author), Jomaa Chemkhi (Author), Hamide Aslan (Author), Shaden Kamhawi (Author), Afif Ben Salah (Author), Hechmi Louzir (Author), Jesus G Valenzuela (Author), Melika Ben Ahmed (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:During a blood meal, female sand flies, vectors of Leishmania parasites, inject saliva into the host skin. Sand fly saliva is composed of a large variety of components that exert different pharmacological activities facilitating the acquisition of blood by the insect. Importantly, protein...