The global prevalence of Trichuris trichiura infection in humans (2010-2023): A systematic review and meta-analysis

• Main Authors: Hamed Behniafar (Author), Mahdi Sepidarkish (Author), Mehrdad Jafari Tadi (Author), Soghra Valizadeh (Author), Mostafa Gholamrezaei (Author), Faezeh Hamidi (Author), Hossein Pazoki (Author), Faezeh Alizadeh (Author), Nazanin Kianifard (Author), Morteza Sheikhi Nooshabadi (Author), Kimia Bagheri (Author), Faezeh Hemmati (Author), Taha Hemmati (Author), Neda Ahmazadeh Tori (Author), Abdelmonem Siddiq (Author), Ali Rostami (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

This systematic review and meta-analysis study aimed to evaluate global Trichuris infection prevalence, assessing progress towards the WHO's 2030 target. We searched international databases from 2010-2023, categorizing data by regions and socio-economic variables using a random-effects model. Analyzing 757 articles covering 7154,842 individuals from 78 countries, the study found a pooled global prevalence of (6.64-7.57%), with the highest rates in the Caribbean (21.72%; 8.90-38.18%) and South-East Asia (20.95; 15.71-26.71%) regions. Southern Africa (9.58; 2.11-21.46%), Latin America (9.58; 2.11-21.46%), and Middle Africa Middle Africa (8.94; 6.31-11.98%) also exhibited high prevalence. Eastern Europe had the lowest prevalence at 0.16% (0.09-0.24). Approximately 513 (480−547) million people worldwide were estimated to harbor Trichuris. Moreover ∼1.5% of people tested worldwide (2010-2023) had a moderate to heavy intensity of infection. The study emphasizes the persistent global health threat of Trichuris infection, urging tailored strategies for effective control and prevention on a global scale.

Item Description

1876-0341
10.1016/j.jiph.2024.03.005