The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture

• Auteurs principaux: Anne Bruggemans (Auteur), Gerlinde Vansant (Auteur), Paulien Van de Velde (Auteur), Zeger Debyser (Auteur)
• Format: Livre
• Publié: Elsevier, 2023-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

A better understanding of HIV-1 latency is a research priority in HIV cure research. Conversely, little is known about the latency characteristics of HIV-2, the closely related human lentivirus. Though both viruses cause AIDS, HIV-2 infection progresses more slowly with significantly lower viral loa...