Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation.

• Main Authors: Piero Olliaro (Author), Max Grogl (Author), Marina Boni (Author), Edgar M Carvalho (Author), Houda Chebli (Author), Mamoudou Cisse (Author), Ermias Diro (Author), Gláucia Fernandes Cota (Author), Astrid C Erber (Author), Endalamaw Gadisa (Author), Farhad Handjani (Author), Ali Khamesipour (Author), Alejandro Llanos-Cuentas (Author), Liliana López Carvajal (Author), Lise Grout (Author), Badre Eddine Lmimouni (Author), Mourad Mokni (Author), Mohammad Sami Nahzat (Author), Afif Ben Salah (Author), Yusuf Ozbel (Author), Juan Miguel Pascale (Author), Nidia Rizzo Molina (Author), Joelle Rode (Author), Gustavo Romero (Author), José Antonio Ruiz-Postigo (Author), Nancy Gore Saravia (Author), Jaime Soto (Author), Soner Uzun (Author), Vahid Mashayekhi (Author), Ivan Dario Vélez (Author), Florian Vogt (Author), Olga Zerpa (Author), Byron Arana (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess treatment effects. A sizable number of trials conducted over the years has generated only weak evidence backing current treatment recommendations, as shown by systematic reviews...