NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)
NADPH oxidases (NOX) constitute the main reactive oxygen species (ROS) source in blood vessels. An oxidative stress situation due to ROS overproduction can lead into endothelial dysfunction, a molecular mechanism that precedes cardiovascular diseases (CVDs) such as atherosclerosis, myocardial infarc...
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Main Authors: | Javier Marqués (Author), Joaquín Fernández-Irigoyen (Author), Elena Ainzúa (Author), María Martínez-Azcona (Author), Adriana Cortés (Author), Carmen Roncal (Author), Josune Orbe (Author), Enrique Santamaría (Author), Guillermo Zalba (Author) |
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Format: | Book |
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MDPI AG,
2022-10-01T00:00:00Z.
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