Precision medicine in regulatory decision making: Biomarkers used for patient selection in European Public Assessment Reports from 2018 to 2020

• Main Authors: Elisabeth Bakker (Author), Viktoriia Starokozhko (Author), Jet W. M. Kraaijvanger (Author), Hiddo J. L. Heerspink (Author), Peter G. M. Mol (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Biomarkers can guide precision medicine in clinical trials and practice. They can increase clinical trials' efficiency through selection of study populations more likely to benefit from treatment, thus increasing statistical power and reducing sample size requirements or study duration...