Treponema pallidum induces the polarization of macrophages via macrophage-derived exosomes

• Main Authors: Chunchan ZHENG (Author), Jiahao XIE (Author), Ruitao ZOU (Author), Guiyue CAI (Author), Sujun LUO (Author), Na WEI (Author), Sirui LI (Author), Rongyi CHEN (Author)
• Format: Book
• Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To explore the effect of Treponema pallidum (Tp) -induced exosomes (EXOTp) by macrophages on macrophage polarization. Methods Human monocyte-macrophages (THP-1) were induced into macrophages, followed by stimulation with or without Tp for 24 h. After changing medium, cells were cultured fo...