Synthesis of cyclo-L-prolyl-glycine and study of its anti-parkinsonian activity

• Autors principals: Ksenia Koliasnikova (Autor), Anna Golubyatnikova (Autor), Alexey Rebeko (Autor), Marina Vukolova (Autor), Polina Povarnina (Autor), Elena Kuznetsova (Autor)
• Format: Llibre
• Publicat: LLC "Publisher OKI", 2019-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The aim of the work was to develop an optimal scheme for the synthesis of substance of cyclo-L-prolylglycine neuropeptide (CPG), a potential drug useful for the integrated treatment of psychiatric pathologies, including anxiety, depressive disorders and cognitive impairment. Two 4-stage CPG synthesi...