Personalizing Colon Cancer Therapeutics: Targeting Old and New Mechanisms of Action
The use of pharmaceuticals for colon cancer treatment has been increasingly personalized, in part due to the development of new molecular tools. In this review, we discuss the old and new colon cancer chemotherapeutics, and the parameters that have been shown to be predictive of efficacy and safety...
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| Main Authors: | , |
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| Format: | Book |
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MDPI AG,
2013-08-01T00:00:00Z.
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| 001 | doaj_f0851ab3ad534b6886ed1e752dc3ae78 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Wafik S. El-Deiry |e author |
| 700 | 1 | 0 | |a Christina Leah B. Kline |e author |
| 245 | 0 | 0 | |a Personalizing Colon Cancer Therapeutics: Targeting Old and New Mechanisms of Action |
| 260 | |b MDPI AG, |c 2013-08-01T00:00:00Z. | ||
| 500 | |a 10.3390/ph6080988 | ||
| 500 | |a 1424-8247 | ||
| 520 | |a The use of pharmaceuticals for colon cancer treatment has been increasingly personalized, in part due to the development of new molecular tools. In this review, we discuss the old and new colon cancer chemotherapeutics, and the parameters that have been shown to be predictive of efficacy and safety of these chemotherapeutics. In addition, we discuss how alternate pharmaceuticals have been developed in light of a potential lack of response or resistance to a particular chemotherapeutic. | ||
| 546 | |a EN | ||
| 690 | |a colorectal cancer | ||
| 690 | |a personalized medicine | ||
| 690 | |a genetic polymorphisms | ||
| 690 | |a Medicine | ||
| 690 | |a R | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Pharmaceuticals, Vol 6, Iss 8, Pp 988-1038 (2013) | |
| 787 | 0 | |n http://www.mdpi.com/1424-8247/6/8/988 | |
| 787 | 0 | |n https://doaj.org/toc/1424-8247 | |
| 856 | 4 | 1 | |u https://doaj.org/article/f0851ab3ad534b6886ed1e752dc3ae78 |z Connect to this object online. |