The presence of TNF-α and TNFR1 in aseptic root resorption. A preliminary study

Background: It is hypothesised that osteoprotegerin (OPG), as an osteoclast antagonist, may offer molecular control over the process of orthodontic root resorption. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts and odont...

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Main Authors: Curl Linda (Author), Sampson Wayne (Author)
Format: Book
Published: Sciendo, 2011-11-01T00:00:00Z.
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100 1 0 |a Curl Linda  |e author 
700 1 0 |a Sampson Wayne  |e author 
245 0 0 |a The presence of TNF-α and TNFR1 in aseptic root resorption. A preliminary study 
260 |b Sciendo,   |c 2011-11-01T00:00:00Z. 
500 |a 2207-7480 
500 |a 10.2478/aoj-2011-0013 
520 |a Background: It is hypothesised that osteoprotegerin (OPG), as an osteoclast antagonist, may offer molecular control over the process of orthodontic root resorption. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts and odontoclasts when given at a recommended dosage of 2.5 mg/kg. It was considered that traumatically-induced PDL inflammation produces mediators and cytokines with the ability to stimulate clast cell differentiation and counter the effects of OPG. 
546 |a EN 
690 |a Dentistry 
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786 0 |n Australasian Orthodontic Journal, Vol 27, Iss 2, Pp 102-109 (2011) 
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787 0 |n https://doaj.org/toc/2207-7480 
856 4 1 |u https://doaj.org/article/f09d644596484e75b82f5be91b0a28b0  |z Connect to this object online.