The presence of TNF-α and TNFR1 in aseptic root resorption. A preliminary study
Background: It is hypothesised that osteoprotegerin (OPG), as an osteoclast antagonist, may offer molecular control over the process of orthodontic root resorption. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts and odont...
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Sciendo,
2011-11-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_f09d644596484e75b82f5be91b0a28b0 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Curl Linda |e author |
700 | 1 | 0 | |a Sampson Wayne |e author |
245 | 0 | 0 | |a The presence of TNF-α and TNFR1 in aseptic root resorption. A preliminary study |
260 | |b Sciendo, |c 2011-11-01T00:00:00Z. | ||
500 | |a 2207-7480 | ||
500 | |a 10.2478/aoj-2011-0013 | ||
520 | |a Background: It is hypothesised that osteoprotegerin (OPG), as an osteoclast antagonist, may offer molecular control over the process of orthodontic root resorption. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts and odontoclasts when given at a recommended dosage of 2.5 mg/kg. It was considered that traumatically-induced PDL inflammation produces mediators and cytokines with the ability to stimulate clast cell differentiation and counter the effects of OPG. | ||
546 | |a EN | ||
690 | |a Dentistry | ||
690 | |a RK1-715 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Australasian Orthodontic Journal, Vol 27, Iss 2, Pp 102-109 (2011) | |
787 | 0 | |n https://doi.org/10.2478/aoj-2011-0013 | |
787 | 0 | |n https://doaj.org/toc/2207-7480 | |
856 | 4 | 1 | |u https://doaj.org/article/f09d644596484e75b82f5be91b0a28b0 |z Connect to this object online. |