Pilocarpine-Induced Status Epilepticus Is Associated with P-Glycoprotein Induction in Cardiomyocytes, Electrocardiographic Changes, and Sudden Death

• Main Authors: Jerónimo Auzmendi (Author), Bruno Buchholz (Author), Jimena Salguero (Author), Carlos Cañellas (Author), Jazmín Kelly (Author), Paula Men (Author), Marcela Zubillaga (Author), Alicia Rossi (Author), Amalia Merelli (Author), Ricardo J. Gelpi (Author), Alberto J. Ramos (Author), Alberto Lazarowski (Author)
• Format: Book
• Published: MDPI AG, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sudden unexpected death in epilepsy (SUDEP) is the major cause of death in those patients suffering from refractory epilepsy (RE), with a 24-fold higher risk relative to the normal population. SUDEP risk increases with seizure frequency and/or seizure-duration as in RE and Status Epilepticus (SE). P...