Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review

Bone tissue engineering (BTE) is a promising approach for repairing and regenerating damaged bone tissue, using stem cells and scaffold structures. Among various stem cell sources, dental pulp stem cells (DPSCs) have emerged as a potential candidate due to their multipotential capabilities, ability...

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Main Authors: Xiaolei Bai (Author), Ruijue Cao (Author), Danni Wu (Author), Huicong Zhang (Author), Fan Yang (Author), Linhong Wang (Author)
Format: Book
Published: Hindawi Limited, 2023-01-01T00:00:00Z.
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100 1 0 |a Xiaolei Bai  |e author 
700 1 0 |a Ruijue Cao  |e author 
700 1 0 |a Danni Wu  |e author 
700 1 0 |a Huicong Zhang  |e author 
700 1 0 |a Fan Yang  |e author 
700 1 0 |a Linhong Wang  |e author 
245 0 0 |a Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review 
260 |b Hindawi Limited,   |c 2023-01-01T00:00:00Z. 
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520 |a Bone tissue engineering (BTE) is a promising approach for repairing and regenerating damaged bone tissue, using stem cells and scaffold structures. Among various stem cell sources, dental pulp stem cells (DPSCs) have emerged as a potential candidate due to their multipotential capabilities, ability to undergo osteogenic differentiation, low immunogenicity, and ease of isolation. This article reviews the biological characteristics of DPSCs, their potential for BTE, and the underlying transcription factors and signaling pathways involved in osteogenic differentiation; it also highlights the application of DPSCs in inducing scaffold tissues for bone regeneration and summarizes animal and clinical studies conducted in this field. This review demonstrates the potential of DPSC-based BTE for effective bone repair and regeneration, with implications for clinical translation. 
546 |a EN 
690 |a Internal medicine 
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786 0 |n Stem Cells International, Vol 2023 (2023) 
787 0 |n http://dx.doi.org/10.1155/2023/7357179 
787 0 |n https://doaj.org/toc/1687-9678 
856 4 1 |u https://doaj.org/article/f0b09a58f0de4060b728c74b0a28c6a1  |z Connect to this object online.