Trypanosoma brucei Invasion and T-Cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes.

• Main Authors: Claudia Laperchia (Author), Maria Palomba (Author), Paul F Seke Etet (Author), Jean Rodgers (Author), Barbara Bradley (Author), Paul Montague (Author), Gigliola Grassi-Zucconi (Author), Peter G E Kennedy (Author), Marina Bentivoglio (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has been recently questioned. Furthermore, the relations...