The Successful Treatment of a Case of Linear Psoriasis with Ixekizumab

Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biologic...

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Main Authors: Sara Ghoneim (Author), Alvaro J. Ramos-Rodriguez (Author), Fernando Vazquez de Lara (Author), Lauren Bonomo (Author)
Format: Book
Published: Hindawi Limited, 2017-01-01T00:00:00Z.
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Summary:Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biological agents reported in the literature. We report a case of a 25-year-old African-American female who presented with asymptomatic hyperkeratotic papules along the lines of Blaschko and was subsequently diagnosed with linear psoriasis. After failing conventional treatment regimens, the patient received a trial of ixekizumab with complete resolution of cutaneous lesions reported after 4 months and only 8 doses of the anti-IL-17 biologic agent.
Item Description:2090-6463
2090-6471
10.1155/2017/3280215