IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes
Elevated interleukin (IL)-1 concentrations in synovial fluid have been implicated in joint bone and cartilage destruction. Previously, we showed that IL-1β stimulated the expression of prostaglandin (PG) receptor EP4 via increased PGE2 production. However, the effect of IL-1β on osteoclast formation...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2009-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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