Novel piperazine-chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation

New piperazine-chalcone hybrids and related pyrazoline derivatives have been designed and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. The National Cancer Institute (NCI) has selected six compounds to evaluate their antiproliferative activity in vitro...

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Bibliographic Details
Main Authors: Marwa F. Ahmed (Author), Eman Y. Santali (Author), Radwan El-Haggar (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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