Cover Image

Peroxisome proliferator-activated receptor alpha plays a crucial role in behavioral repetition and cognitive flexibility in mice

Background/objectives: Nuclear peroxisome proliferator activated receptor-α (PPAR-α) plays a fundamental role in the regulation of lipid homeostasis and is the target of medications used to treat dyslipidemia. However, little is known about the role of PPAR-α in mouse behavior. Methods: To investiga...

Full description

Saved in:

Bibliographic Details
Main Authors:	Giuseppe D'Agostino (Author), Claudia Cristiano (Author), David J. Lyons (Author), Rita Citraro (Author), Emilio Russo (Author), Carmen Avagliano (Author), Roberto Russo (Author), Giuseppina Mattace Raso (Author), Rosaria Meli (Author), Giovambattista De Sarro (Author), Lora K. Heisler (Author), Antonio Calignano (Author)
Format:	Book
Published:	Elsevier, 2015-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Analgesic and Anti-Inflammatory Effects of Perampanel in Acute and Chronic Pain Models in Mice: Interaction With the Cannabinergic System
by: Carmen De Caro, et al.
Published: (2021)

Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders
by: Martina Tallarico, et al.
Published: (2023)

The Pressing Issue of Micro- and Nanoplastic Contamination: Profiling the Reproductive Alterations Mediated by Oxidative Stress
by: Maria Carmela Ferrante, et al.
Published: (2022)

Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors
by: Carmen De Caro, et al.
Published: (2020)

The Hepatic Mitochondrial Alterations Exacerbate Meta-Inflammation in Autism Spectrum Disorders
by: Giovanna Trinchese, et al.
Published: (2022)

Sex Differences in Hepatic Inflammation, Lipid Metabolism, and Mitochondrial Function Following Early Lipopolysaccharide Exposure in Epileptic WAG/Rij Rats
by: Stefania Melini, et al.
Published: (2024)

Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism
by: L. Di Cesare Mannelli, et al.
Published: (2013)

Colchicine in Managing Skin Conditions: A Systematic Review
by: Stefano Dastoli, et al.
Published: (2022)

Phaseolus vulgaris extract ameliorates high-fat diet-induced colonic barrier dysfunction and inflammation in mice by regulating peroxisome proliferator-activated receptor expression and butyrate levels
by: Carmen Avagliano, et al.
Published: (2022)

Peroxisomal Disorders
by: J Gordon Millichap
Published: (1988)

Peroxisomal Disorders
by: J Gordon Millichap
Published: (1988)

Peroxisomal Disorders
by: J Gordon Millichap
Published: (1990)

Peroxisome Proliferator-Activated Receptors (PPARs) and Oxidative Stress in Physiological Conditions and in Cancer
by: Giuliana Muzio, et al.
Published: (2021)

Peroxisomal Disorders Diagnosis
by: J Gordon Millichap
Published: (1998)

Effect of Statins on Lung Cancer Molecular Pathways: A Possible Therapeutic Role
by: Gianmarco Marcianò, et al.
Published: (2022)

Antiseizure Effects of Cannabidiol Leading to Increased Peroxisome Proliferator-Activated Receptor Gamma Levels in the Hippocampal CA3 Subfield of Epileptic Rats
by: Anna-Maria Costa, et al.
Published: (2022)

Direct Oral Anticoagulants: From Randomized Clinical Trials to Real-World Clinical Practice
by: Roberta Roberti, et al.
Published: (2021)

Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures [Corrigendum]
by: Mumoli L, et al.
Published: (2015)

Brivaracetam: review of its pharmacology and potential use as adjunctive therapy in patients with partial onset seizures
by: Mumoli L, et al.
Published: (2015)

Crucial Instances
by: Wharton, Edith, 1862-1937

Momento crucial
by: Agustí Boixeda de Miquel
Published: (2012)

The Metabolic Role of Peroxisome in Health and Disease
Published: (2022)

A Solitary Pinkish Nodule on the Abdomen: A Quiz
by: Roberto Russo, et al.
Published: (2024)

Oral Bisphenol A Worsens Liver Immune-Metabolic and Mitochondrial Dysfunction Induced by High-Fat Diet in Adult Mice: Cross-Talk between Oxidative Stress and Inflammasome Pathway
by: Claudio Pirozzi, et al.
Published: (2020)

Repetitions
by: Abbott, Scott
Published: (2013)

Repetitions
by: Abbott, Scott
Published: (2013)

Peroxisomal biogenesis disorders in Zellweger syndrome spectrum: diagnosis, monitoring and treatment according to the recommendations of the Global Foundation for Peroxisomal Disorders
by: M.A. Gonchar, et al.
Published: (2018)

The Crucial Moment 1911
by: Craddock, Charles Egbert, 1850-1922

Origin and spatiotemporal dynamics of the peroxisomal endomembrane system
by: Richard A. Rachubinski
Published: (2015)

The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway
by: Alessandro Maugeri, et al.
Published: (2022)

Peroxisomal PEX7 Receptor Affects Cadmium-Induced ROS and Auxin Homeostasis in Arabidopsis Root System
by: Diego Piacentini, et al.
Published: (2021)

The Role of Peroxisome Proliferator-Activated Receptors in Kidney Diseases
by: Jianjun Gao, et al.
Published: (2022)

Functional peroxisomes are required for β-cell integrity in mice
by: Ritesh Kumar Baboota, et al.
Published: (2019)

An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists
by: Rita Citraro, et al.
Published: (2023)

Interactions among Low Dose of Methotrexate and Drugs Used in the Treatment of Rheumatoid Arthritis
by: Marinella Patanè, et al.
Published: (2013)

Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism
by: Claudia Cristiano, et al.
Published: (2022)

Repetition-to-Repetition Differences Using Cluster and Accentuated Eccentric Loading in the Back Squat
by: John P. Wagle, et al.
Published: (2018)

Repetitive DNA Sequences
by: Dion-Côté, Anne-Marie
Published: (2020)

Dysphagia: A practical approach
by: Giuseppina Russo, et al.
Published: (2024)

Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases
by: Francisco A. Monsalve, et al.
Published: (2013)