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Synthesis of Alkyne-Substituted Dihydropyrrolones as Bacterial Quorum-Sensing Inhibitors of <i>Pseudomonas aeruginosa</i>

The Quorum-sensing system in <i>Pseudomonas aeruginosa</i> is responsible for the pathogenicity and the production of virulence factors and biofilm formation. Dihydropyrrolones were previously found to act as inhibitors of QS-dependent bacterial phenotypes. In this study, a range of dihy...

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Main Authors: Basmah Almohaywi (Author), Tsz Tin Yu (Author), George Iskander (Author), Shekh Sabir (Author), Mohan Bhadbhade (Author), David StC. Black (Author), Naresh Kumar (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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