Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy

• Main Authors: Ming-Wei Lin (Author), Chi Chien Lin (Author), Yi-Hung Chen (Author), Han-Bin Yang (Author), Shih-Ya Hung (Author)
• Format: Book
• Published: MDPI AG, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson’s disease (PD) is a neurodegenerative disease, which is associated with mitochondrial dysfunction and abnormal protein accumulation. No treatment can stop or slow PD. Autophagy inhibits neuronal death by removing damaged mitochondria and abnormal protein aggregations. Celastrol i...