Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome
Netherton syndrome is a monogenic autosomal recessive disorder primarily characterized by the detachment of the uppermost layer of the epidermis, the stratum corneum. It results from mutations in the SPINK5 gene, which codes for a kallikrein inhibitor. Uncontrolled kallikrein activity leads to prema...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2020-05-01T00:00:00Z.
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