Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokinetic-pharmacodynamic model.

• Main Authors: Luka Verrest (Author), Séverine Monnerat (Author), Ahmed M Musa (Author), Jane Mbui (Author), Eltahir A G Khalil (Author), Joseph Olobo (Author), Monique Wasunna (Author), Wan-Yu Chu (Author), Alwin D R Huitema (Author), Henk D F H Schallig (Author), Fabiana Alves (Author), Thomas P C Dorlo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>With the current treatment options for visceral leishmaniasis (VL), recrudescence of the parasite is seen in a proportion of patients. Understanding parasite dynamics is crucial to improving treatment efficacy and predicting patient relapse in cases of VL. This study a...