Epigallocatechin-3-gallate reduces inflammation induced by calcium pyrophosphate crystals in vitro.

• Main Authors: Francesca eOliviero (Author), Paolo eSfriso (Author), Anna eScanu (Author), Ugo eFiocco (Author), Paolo eSpinella (Author), Leonardo ePunzi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although osteoarthritis (OA) is defined as a cartilage disease, synovitis involving mononuclear cell infiltration and overexpression of proinflammatory mediators is common in early and late OA. Calcium crystals deposition is thought to be a factor that likely contributes to synovial inflammation.In...