Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats

• Main Authors: Hany H. Arab (Author), Ali Khames (Author), Mostafa K. Mohammad (Author), Shuruq E. Alsufyani (Author), Ahmed M. Ashour (Author), Azza A. K. El-Sheikh (Author), Hany W. Darwish (Author), Amany M. Gad (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Meloxicam has shown significant neuroprotection in experimental models of stroke, Alzheimer's disease, and Parkinson's disease. However, the potential of meloxicam to treat depression-like neuropathology in a chronic restraint stress (CRS) model and the associated molecular changes has bee...