Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature

Central giant cell granuloma (CGCG) is a benign non-neoplastic intraosseous lesion mainly found in the anterior mandible. It is characterized by multinucleated giant cells, representing osteoclasts or macrophages. Central odontogenic fibroma (COF) is an uncommon benign lesion of the jaws. It origina...

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Bibliographic Details
Main Authors: Monir Moradzadeh (Author), Abbas Karimi (Author), Hassan Mirmohammad Sadeghi (Author), Samira Derakhshan (Author), Seyed Mobin Tafreshi (Author), Samar Jalali (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2022-01-01T00:00:00Z.
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LEADER 00000 am a22000003u 4500
001 doaj_f21c6e46ebe64d04b50e8eec2973cd2f
042 |a dc 
100 1 0 |a Monir Moradzadeh  |e author 
700 1 0 |a Abbas Karimi  |e author 
700 1 0 |a Hassan Mirmohammad Sadeghi  |e author 
700 1 0 |a Samira Derakhshan  |e author 
700 1 0 |a Seyed Mobin Tafreshi  |e author 
700 1 0 |a Samar Jalali  |e author 
245 0 0 |a Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature 
260 |b Tehran University of Medical Sciences,   |c 2022-01-01T00:00:00Z. 
500 |a 10.18502/fid.v18i44.8340 
500 |a 2676-296X 
520 |a Central giant cell granuloma (CGCG) is a benign non-neoplastic intraosseous lesion mainly found in the anterior mandible. It is characterized by multinucleated giant cells, representing osteoclasts or macrophages. Central odontogenic fibroma (COF) is an uncommon benign lesion of the jaws. It originates from the odontogenic ectomesenchyme. In rare cases, COF may accompany a CGCG. To date, 49 cases of COF accompanied by CGCG-like lesions have been reported in the literature. In this paper, we present another case of COF-CGCG in a 46-year-old female. The lesion was located in the posterior mandible. Excisional biopsy was carried out, and histopathological analysis revealed multinucleated giant cells with numerous strands of odontogenic epithelium. A literature review of previously reported cases was also performed. 
546 |a EN 
690 |a Granuloma 
690 |a Giant Cell; 
690 |a Fibroma; 
690 |a Odontogenic Tumors 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Frontiers in Dentistry, Vol 18 (2022) 
787 0 |n https://fid.tums.ac.ir/index.php/fid/article/view/3760 
787 0 |n https://doaj.org/toc/2676-296X 
856 4 1 |u https://doaj.org/article/f21c6e46ebe64d04b50e8eec2973cd2f  |z Connect to this object online.