A Novel Dual-Function Nitric Oxide Donor Therapy for Preeclampsia-A Proof-of-Principle Study in a Murine Model

• Main Authors: Diana Pintye (Author), Réka E. Sziva (Author), Lauren A. Biwer (Author), Esilida Sula Karreci (Author), Sonako Jacas (Author), Maxim Mastyugin (Author), Marianna Török (Author), Brett C. Young (Author), Prakash Jagtap (Author), Garry J. Southan (Author), Iris Z. Jaffe (Author), Zsuzsanna K. Zsengellér (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background</b>: Preeclampsia (PE) is a hypertensive disorder of pregnancy that is associated with substantial morbidity and mortality for the mother and fetus. Reduced nitric oxide bioavailability and oxidative stress contribute to the maternal and fetal pathophysiology of PE. In this...