Intrauterine IPEX

• Главные авторы: Magda Carneiro-Sampaio (Автор), Carlos Alberto Moreira-Filho (Автор), Silvia Yumi Bando (Автор), Jocelyne Demengeot (Автор), Antonio Coutinho (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

IPEX is one of the few Inborn Errors of Immunity that may manifest in the fetal period, and its intrauterine forms certainly represent the earliest human autoimmune diseases. Here, we review the clinical, histopathologic, and genetic findings from 21 individuals in 11 unrelated families, with nine d...