Identifying novel sphingosine kinase 1 inhibitors as therapeutics against breast cancer

• Main Authors: Faez Iqbal Khan (Author), Dakun Lai (Author), Razique Anwer (Author), Iffat Azim (Author), Mohd Kalim Ahmad Khan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sphingosine kinase 1 (SphK1) is a promising therapeutic target against several diseases including mammary cancer. The aim of present work is to identify a potent lead compound against breast cancer using ligand-based virtual screening, molecular docking, MD simulations, and the MMPBSA calculations....