Predictive Simulations in Preclinical Oncology to Guide the Translation of Biologics

• मुख्य लेखकों: Shujun Dong (लेखक), Ian Nessler (लेखक), Anna Kopp (लेखक), Baron Rubahamya (लेखक), Greg M. Thurber (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Preclinical in vivo studies form the cornerstone of drug development and translation, bridging in vitro experiments with first-in-human trials. However, despite the utility of animal models, translation from the bench to bedside remains difficult, particularly for biologics and agents with unique me...