In vitro wound healing of tumor cells: inhibition of cell migration by selected cytotoxic alkaloids

• Main Authors: Xiaojuan Wang (Author), Charlotte Caroline Decker (Author), Laura Zechner (Author), Sonja Krstin (Author), Michael Wink (Author)
• Formato: Livro
• Publicado em: BMC, 2019-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Cell migration is involved in several pathological processes such as tumor invasion, neoangiogenesis and metastasis. Microtubules are needed in directional migration. Methods To investigate the effects of microtubule-binding agents (paclitaxel, vinblastine, colchicine, podophyllo...