The Segregated Intestinal Flow Model (SFM) for Drug Absorption and Drug Metabolism: Implications on Intestinal and Liver Metabolism and Drug-Drug Interactions
The properties of the segregated flow model (SFM), which considers split intestinal flow patterns perfusing an active enterocyte region that houses enzymes and transporters (<20% of the total intestinal blood flow) and an inactive serosal region (>80%), were compared to those of the traditiona...
Saved in:
Main Authors: | K. Sandy Pang (Author), H. Benson Peng (Author), Keumhan Noh (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human
by: Yunhai Cui, et al.
Published: (2020) -
Regional Intestinal Drug Absorption Biopharmaceutics and Drug Formulation
Published: (2022) -
Regional Intestinal Drug Absorption: Biopharmaceutics and Drug Formulation
by: Arik Dahan, et al.
Published: (2021) -
Involvement of Transporters in Intestinal Drug-Drug Interactions of Oral Targeted Anticancer Drugs Assessed by Changes in Drug Absorption Time
by: David Malnoë, et al.
Published: (2022) -
Machine Learning Predicts Drug Metabolism and Bioaccumulation by Intestinal Microbiota
by: Laura E. McCoubrey, et al.
Published: (2021)